Lidocaine Base 137-58-6 for the treatment of ventricular arrhythmias
Lidocaine Base Profile
Product Name: Lidocaine Base
CAS Number: 137-58-6
Molecular Formula: C14H23N2O
Molecular Weight: 235.3447
Melting point :66-69 °C
solubility ethanol: 4 mg/mL
Appearance: White crystaline powder
Lidocaine Base Description
Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.
Inhaled lidocaine can be used as an antitussive (cough suppressor) acting peripherally to reduce the cough reflex. This application can be implemented as a safety and comfort measure for patients who have to be intubated, as it reduces the incidence of coughing and any tracheal damage it might cause when emerging from anesthesia.
Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.
Lidocaine Base Main functions are as follows:
2. Treating Epilepsy.
3. Treating Asthma.
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