Fenoprofen Phenaceti Powder 31879-05-7 Local Anesthetics Fenoprofen

Product Description
phenacet

–EINECS:200-533-0

–Molecular Formula:C10H13NO2

–Molecular Weight:179.22

–Density:1.099 g/cm3

–Melting Point:133-138ºC

–Flash Point:355.1 °C at 760 mmHg

–Storage Temperature:2-8°C

–Refractive index:1.505 (20 C)

–Solubility:0.076 g/100 mL

–Appearance:white crystalline powder

–Stability:Stable. Incompatible with strong oxidizing agents, strong acids.

Descriptions:
phenacet is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenaceti.

Applications:
phenacet was widely used until the third quarter of the twentieth century, often in the form of an “A.P.C.” or aspirin-phenaceti compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent’s APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenaceti in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)). It was also banned in India.As a result some branded, previously phenaceti-based preparations continued to be sold, but with the phenaceti replaced by safer alternatives. A popular brand of phenaceti was Roche’s Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and . Coricidin was also reformulated without phenaceti. Paracetamol is a metabolite of phenacetiwith similar analgesic and antipyretic effects, but the new formulation has not been found to have phenaceti’s carcinogenicity.

phenacet is now being used as a cutting agent to adulterate  in the UK and Canada, owing to the similar physical features of the two drugs.

Due to low cost phenaceti is used for research into the physical and refractive properties of crystals.
It is an ideal compound for this type of research

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1,4-D-H-E-A
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Author: chemicals

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