Factory Supply High Quality 99% 5-Fluorouracil CAS: 51-21-8 

Product Description
Factory Supply High Quality 99% 5-Fluorouracil CAS: 51-21-8

Product Name: 5-Fluorouracil
Synonyms: [180]-5-Fluorouracil;2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;2,4-dioxo-5-fluoropyrimidine;3h)-pyrimidinedione,5-fluoro-4(1h;5-faracil;5-Flouracyl;5-fluor-2,4(1h,3h)-pyrimidindion;5-Fluor-2,4-dihydroxypyrimidin
CAS: 51-21-8
MW: 130.08
EINECS: 200-085-6
Product Categories: Pharmaceutical Raw Materials;PYRIMIDINE;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Phenylacetic acid;Tegafur Carmofur;Nucleotides and Nucleosides;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Nucleotides;API’s;Antitumour;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Inhibitor;Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;CARAC;Inhibitors
Mol File: 51-21-8.mol
5-Fluorouracil Chemical Properties
mp 282-286 °C (dec.)(lit.)
bp 190-200°C/0.1mmHg
storage temp. Store at 0-5
solubility H2O: 10 mg/mL, clear
form powder
color white
Water Solubility 12.2 g/L 20 ºC
Sensitive Air Sensitive
Merck 14,4181
BRN 127172
Stability: Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference 51-21-8(CAS DataBase Reference)
NIST Chemistry Reference 2,4-Pyrimidinedione, 5-fluoro-(51-21-8)
EPA Substance Registry System 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-(51-21-8)
Safety Information
Hazard Codes Xn,T,C,Xi
Risk Statements 22-20/21/22-52-25
Safety Statements 36-36/37-36/37/39-22-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS YR0350000
F 10-23
Hazard Note Irritant/Highly Toxic
HazardClass 6.1
PackingGroup III
HS Code 29335995
Hazardous Substances Data 51-21-8(Hazardous Substances Data)
General Description White to nearly white crystalline powder; practically odorless. Used as an anti neoplastic drug, chemosterilant for insects.
Application 1. It is used for biochemical studies and antitumor drugs.
2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.
3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.
4. Antimetabolite antitumor drugs.
5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.

Author: chemicals

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