Vortioxetine Hydrobromide Powder
This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.
- Allow at least 2 weeks to elapse between discontinuance of an MAO inhibitor intended to treat psychiatric disorders and initiation of vortioxetine and allow at least 3 weeks to elapse between discontinuance of vortioxetine and initiation of MAO inhibitor therapy intended to treat psychiatric disorders.(See Contraindications and Serotonin Syndrome under Cautions and also see Specific Drugs under Interactions.)
- Monitor for possible worsening of depression, suicidality, or unusual changes in behavior, especially at the beginning of therapy or during periods of dosage adjustments.(See Worsening of Depression and Suicidality Risk under Cautions.)
- Although vortioxetine can be abruptly discontinued, transient adverse reactions (including headache, muscle tension, mood swings, sudden outbursts of anger, dizziness, runny nose) reported in the first week following abrupt discontinuance of dosages of 15 or 20 mg daily.Manufacturer recommends decreasing dosage to 10 mg daily for one week before full discontinuance in patients receiving 15 or 20 mg of the drug daily, if possible.